Interstitial Lung Disease in a Glass Industry Worker: A Rare Case Report

  • Seshagiri Rao Damaraju Associate Professor, Department of Pulmonology
  • Raghavendra Rao Manukonda Professor & Head, Department of Pulmonology
Keywords: Glass industry worker, Investigation profi le, Occupational lung diseases, Respiratory illness, Steroid inhalers


Occupational lung diseases are caused by long-term exposure to irritating or toxic agents in the workplace for the workers.
Epidemiologic studies in humans suggest that there is no direct evidence of chronic lung disease associated with glass
exposure. However, rare cases of granulomatous lung disease have been reported. We report a case of a 27-year-old male
patient working in a glass manufacturing industry with recent onset of breathlessness and cough. Chest X-ray, high-resolution
computed tomography revealed nodular opacities. Bronco-alveolar lavage sample and lung biopsy revealed histopathological
examination report. Patient is being managed by corticosteroid inhalers and respiratory physiotherapy. Change in profession
has been advised for prevention of future exposure.

Author Biographies

Seshagiri Rao Damaraju, Associate Professor, Department of Pulmonology

Rangaraya Medical Collage, Kakinada, Andhra Pradesh, India

Raghavendra Rao Manukonda, Professor & Head, Department of Pulmonology

Rangaraya Medical Collage, Kakinada, Andhra Pradesh, India


1. Lippmann M. Effects of fi ber characteristics on lung deposition, retention,
and disease. Environ Health Perspect 1990;88:311-7.
2. Ferreira AS, Moreira VB, Castro MC, Soares PJ, Algranti E, Andrade LR.
Case report: analytical electron microscopy of lung granulomas associated
with exposure to coating materials carried by glass wool fi bers. Environ
Health Perspect 2010;118:249-52.
3. Guber A, Lerman S, Lerman Y, Ganor E, Trajber I, Edelstein E, et al.
Pulmonary fi brosis in a patient with exposure to glass wool fi bers. Am J Ind
Med 2006;49:1066-9.
4. Marsh GM, Youk AO, Stone RA, Buchanich JM, Gula MJ, Smith TJ,
et al. Historical cohort study of US man-made vitreous fi ber production
workers: I. 1992 fi berglass cohort follow-up: initial fi ndings. J Occup
Environ Med 2001;43:741-56.
5. Morgan RW, Bratsberg JA. Mortality study of fi brous glass production
workers. Arch Environ Health 1981;36:179-83.
6. Baan RA, Grosse Y. Man-made mineral (vitreous) fi bres: Evaluations
of cancer hazards by the IARC Monographs Programme. Mutat Res
7. Zisman DA, Keane MP, Belperio JA, Strieter RM, Lynch JP rd. Pulmonary
fi brosis. Methods Mol Med 2005;117:3-44.