Incidence of Osteoporosis in Chronic Obstructive Pulmonary Disease Patients in a Tertiary Care Hospital: A Prospective Clinical Study
Background: The purpose of the present study is to know the incidence of osteoporosis in chronic obstructive pulmonary
disease (COPD) patients in relation to its severity and early diagnosis of osteoporosis in COPD patients and its treatment can
change quality of life of the patients.
Methods: A prospective clinical study consisted of 100 COPD patients above 40 years were undertaken to study the incidence
of osteoporosis. Of which, 74 males and 26 females were included in this study. Known COPD patients were assessed by
GOLD criteria of severity.
Results: The study group consisted of 100 patients, of which 74 are males and 26 are females. Incidence of osteopenia and
osteoporosis among males are 16.21% and 60.81% respectively. Incidence of osteopenia and osteoporosis among females
are 19.23% and 50.00% respectively (P > 0.05). Among men incidence of osteoporosis increases with an increase of grading.
It increased from 9.09% for Grade 2 to 81.81% to Grade 4 (P < 0.01). Among women incidence of osteoporosis increases with
increase of grading. It increased from 20.00% for Grade 2 to 70.00% to Grade 4 (P > 0.05). Incidence of osteoporosis is high
among patients on oral steroids 82.97%. Incidence among oral inhaled corticosteroid patients is 51.51% and on no steroids
is 10% (P > 0.05).
Conclusions: In the present study, incidence of severity of osteoporosis increases with increased grading of COPD with high
use of oral steroids. Early diagnosis of osteoporosis in COPD patients with early treatment can change the quality of life.
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