Management of Hollow Viscous Gastric and Duodenal Perforation Cases by Surgical Method versus Non-Operative Management: A Comparative Study
Abstract
Background: Upper gastrointestinal hollow viscous perforation is multifactorial and not fully understood even today. Hollow
viscous perforation of upper gastrointestinal i.e. Gastric and duodenal perforations presents to the causality with acute abdominal
pain and distension, hypotension and prostration.
Aims: The purpose of this study is to compare the outcome in patients with gastric or duodenal perforation by non-operative
management as against defi nitive surgery.
Materials and Methods: A prospective study of upper gastrointestinal hollow viscous perforation cases was undertaken in
Government General Hospital, Kakinada. 100 cases of perforation of duodenum and stomach have been included in this study.
Of them, 70 cases were managed by defi nitive surgery, and 30 cases were unfi t to undergo an anesthetic and surgical line of
management. This group was managed by bilateral fl ank drains. Follow-up regarding recovery was observed.
Results: Maximum age incidence of hollow viscous perforation (gastric and duodenal) is between 35 and 45 years. Maximum
sex incidence is in males - 80%. Of these 30 patients was managed by non-operative method. Non-operative management
was successful in total recovery in 66.66% of patients, which is very signifi cant. Out of the survived cases maximum number
are at the age of 35-45 years.
Conclusions: Non-operative management, by keeping bilateral fl ank drains, is a formidable line of management as an alternative
to surgical management in patients with compromised general condition, unfit for any type of anesthesia.
References
for perforated peptic ulcer in the elderly. Evaluation of factors infl uencing
prognosis. Hepatogastroenterology 2003;50:1956-8.
2. Noguiera C, Silva AS, Santos JN, Silva AG, Ferreira J, Matos E, et al.
Perforated peptic ulcer: Main factors of morbidity and mortality. World J
Surg 2003;27:782-7.
3. Hermansson M, Staël von Holstein C, Zilling T. Surgical approach and
prognostic factors after peptic ulcer perforation. Eur J Surg 1999;165:566-72.
4. Testini M, Portincasa P, Piccinni G, Lissidini G, Pellegrini F, Greco L.
Signifi cant factors associated with fatal outcome in emergency open
surgery for perforated peptic ulcer. World J Gastroenterol 2003;9:2338-40.
5. Svanes C. Trends in perforated peptic ulcer: Incidence, etiology, treatment,
and prognosis. World J Surg 2000;24:277-83.
6. Shan YS, Hsu HP, Hsieh YH, Sy ED, Lee JC, Lin PW. Signifi cance of
intraoperative peritoneal culture of fungus in perforated peptic ulcer. Br J
Surg 2003;90:1215-9.
7. Crofts TJ, Park KG, Steele RJ, Chung SS, Li AK. A randomized trial
of nonoperative treatment for perforated peptic ulcer. N Engl J Med
1989;320:970-3.
8. Berne TV, Donovan AJ. Nonoperative treatment of perforated duodenal
ulcer. Arch Surg 1989;124:830-2.
9. Keane TE, Dillon B, Afdhal NH, McCormack CJ. Conservative management
of perforated duodenal ulcer. Br J Surg 1988;75:583-4.
10. Donovan AJ, Berne TV, Donovan JA. Perforated duodenal ulcer: An
alternative therapeutic plan. Arch Surg 1998;133:1166-71.
11. Marshall C, Ramaswamy P, Bergin FG, Rosenberg IL, Leaper DJ.
Evaluation of a protocol for the non-operative management of perforated
peptic ulcer. Br J Surg 1999;86:131-4.
12. Crofts TJ, Park KG, Steele RJ, Chung SS, Li AK. A randomized trial
of nonoperative treatment for perforated peptic ulcer. N Engl J Med
1989;320:970-3.
13. Katkhouda N, Mavor E, Mason RJ, Campos GM, Soroushyari A, Berne TV.
Laparoscopic repair of perforated duodenal ulcers: Outcome and effi cacy in
30 consecutive patients. Arch Surg 1999;134:845-8.
14. Lee FY, Leung KL, Lai PB, Lau JW. Selection of patients for laparoscopic
repair of perforated peptic ulcer. Br J Surg 2001;88:133-6.
15. Bergamaschi R, Mårvik R, Johnsen G, Thoresen JE, Ystgaard B,
Myrvold HE. Open vs laparoscopic repair of perforated peptic ulcer. Surg
Endosc 1999;13:679-82.