Acute Pancreatitis as a Manifestation of Primary Hyperparathyroidism: An Uncommon Association

Abstract

The manifestation of primary hyperparathyroidism (PHPT) as acute pancreatitis (AP) is a rare entity. We report a case of a
55-year-old female, admitted to the intensive care unit of the general surgery department presenting with features of acute
abdomen with a clinical and radiological diagnosis of AP. Further evaluation revealed hypercalcemia and PHPT due to
parathyroid adenoma. Hypercalcemia due to PHPT plays a vital role in the pathogenesis of pancreatitis. The patient underwent
parathyroidectomy and pathological examination of the parathyroid gland confirmed a parathyroid adenoma. After aggressive
medical management of AP and hypercalcemia, parathyroidectomy has been shown to improve clinical outcomes and prevent
further recurrences of pancreatitis.