Predisposing Factors and Outcome of Fournier’s Gangrene
Introduction: Fournier’s gangrene (FG) is the fulminant necrotizing fasciitis of the perineum and genitalia resulting from polymicrobial infection. This disease is known to be prevalent for many centuries.
Aim: This study aims to study the predisposing factors associated with FG and its outcome.
Materials and Methods: Patients with features of necrotizing fasciitis of the perineal/genital regions were included in the study. The diagnosis was confirmed by clinical examination and detailed history regarding prior history of diabetes mellitus, hypertension, perianal sepsis, urinary retention/extravasation, trauma, and immunodeficiency states was recorded. The mortality and morbidity rates were calculated.
Results: Diabetes was the most common predisposing factor associated with FG (44.4%). Escherichia coli was the most common organism involved both in survivors and non-survivors group. One-third of the patients were infected with multiple species. The mortality rate encountered in our study was 15%.
Conclusion: Early recognition of the pathology and aggressive surgical debridement is the mainstays of the management of FG. Additional strategies to improve wound healing and increase patient survival are also needed.
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