Umbilical Cord Milking Reduces Duration of Inotrope Support in Preterm Infants Less than 32 Weeks of Gestation, Born with Cesarean Section in Comparison to Delayed Cord Clamping

  • Vrushali Vilas Bichkar Yashwantrao Chavan Memorial Hospital, Pimpri, Pune, Maharashtra, India
  • Jayashree Mondkar Lokmanya Tilak Municipal Hospital, Sion, Mumbai, Maharashtra, India
  • Swati Manerkar Lokmanya Tilak Municipal Hospital, Mumbai, Maharashtra, India
  • Swapnil Bhisikar New Era Hospital, Nashik, Maharashtra, India
Keywords: Gestation, Infants, Preterm


Objective: Very preterm infants commonly need inotrope support. We aimed to demonstrate that umbilical cord milking (UCM) would reduce the need for inotropes in preterm infants born with cesarean section in comparison to delayed cord clamping (DCC).
Study Design: We compared the need of inotrope support, in a pilot randomized controlled trial, among preterm infants <32 weeks’ gestation receiving UCM (n = 25) in comparison to those who underwent DCC (n = 24).
Results: Baseline maternal and newborn characteristics were similar. There was a significant reduction in the total duration of inotrope support (P = 0.004) and total duration of respiratory support (P = 0.021) in babies undergoing UCM when compared to those undergoing DCC. Trend toward reduction in incidence of hemodynamically significant patent ductus arteriosus and intraventricular hemorrhage was noted in UCM group.
Conclusion: UCM significantly improved respiratory and hemodynamic stability in preterm infants <32 weeks’ gestation without associated complications.

Author Biographies

Vrushali Vilas Bichkar, Yashwantrao Chavan Memorial Hospital, Pimpri, Pune, Maharashtra, India

Assistant Professor, Department of Pediatrics, 

Jayashree Mondkar, Lokmanya Tilak Municipal Hospital, Sion, Mumbai, Maharashtra, India

Professor and Dean, Department of Neonatology,

Swati Manerkar, Lokmanya Tilak Municipal Hospital, Mumbai, Maharashtra, India

Associate Professor, Department of Neonatology, 

Swapnil Bhisikar, New Era Hospital, Nashik, Maharashtra, India

Consultant Department of Neonatologist, 


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